Neutrophil expression and infiltration into Crohn′s intestine
نویسندگان
چکیده
منابع مشابه
Morphine reduces local cytokine expression and neutrophil infiltration after incision
BACKGROUND Inflammation and nociceptive sensitization are hallmarks of tissue surrounding surgical incisions. Recent studies demonstrate that several cytokines may participate in the enhancement of nociception near these wounds. Since opioids like morphine interact with neutrophils and other immunocytes, it is possible that morphine exerts some of its antinociceptive action after surgical incis...
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Contact hypersensitivity (CHS) is a T cell response to hapten skin challenge of sensitized individuals proposed to be mediated by hapten-primed CD8 cytolytic T cells. Effector CD8 T cell recruitment into hapten challenge sites to elicit CHS requires prior CXCL1- and CXCL2-mediated neutrophil infiltration into the site. We investigated whether neutrophil activities directing hapten-primed CD8 T ...
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In a mouse model of herpes simplex virus (HSV) 1 corneal infection, tissue destruction results from a CD4+ T cell-mediated chronic inflammation, in which interleukin 2 and interferon (IFN) gamma are requisite inflammatory mediators and polymorphonuclear leukocytes (PMN) are the predominant infiltrating cells. In vivo neutralization of IFN-gamma relieved inflammation at least in part through a s...
متن کاملTiming of infiltration of T lymphocytes induced by gluten into the small intestine in coeliac disease.
Jejunal biopsy was performed on control subjects and patients with treated and untreated coeliac disease. Monoclonal antibodies to T lymphocyte surface markers were used to quantify T cell phenotypic subsets in the jejunal mucosa. The patients with untreated coeliac disease had significantly more of both suppressor/cytotoxic and helper/inducer T cells in the surface epithelium than either the c...
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Interstitial granulomatous dermatitis (IGD) with arthritis is a new histological entity first described by Ackerman et al in 1993 [1]. Herein we report a case of IGD with prominent neutrophilic infiltration. A 57-year-old man was referred to our clinic with persistent, systemic, pruritic erythema and papules of four years’ duration. Psoriasis vulgaris was diagnosed and the patient was treated w...
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ژورنال
عنوان ژورنال: Saudi Journal of Gastroenterology
سال: 2005
ISSN: 1319-3767
DOI: 10.4103/1319-3767.33322